Assessing relinquishment of positivity as a central symptom bridging anxiety and depression

J Affect Disord. 2024 Dec 15:367:38-48. doi: 10.1016/j.jad.2024.08.031. Epub 2024 Aug 13.

Abstract

Anxiety and depression are often comorbid and chronic disorders. Previous research indicates that positivity relinquishment is a moderator of anxiety and depression, such that only anxious individuals who endorsed relinquishing positivity were also depressed. We sought to extend those findings by conducting three network analyses with self-report measures of anxiety, depression, activity avoidance, and perceived positivity of avoided activities (N = 104). We pre-registered our hypothesis for the first two networks that relinquishment of positivity would emerge as a central bridge symptom between anxiety and depressive symptoms. After combining redundant nodes, we estimated three networks and investigated the bridge symptoms in each network. Relinquishment of positivity bridged the symptom clusters in the first network, and avoidance of positivity was found to bridge the two symptom clusters of anxiety and depression in networks two and three. Additionally, an anhedonia circuit was uncovered in all three networks in which loss of interest/worthlessness, loss of energy, and loss of pleasure/pessimism connected to anxiety through relinquishment or avoidance. Our findings suggest that both relinquishment of positivity as well as avoidance of positivity could be potential pathways explaining the development and maintenance of anxiety and depression and should be properly targeted in treatment.

Keywords: Anxiety; Avoidance; Depression; Network analysis; Positivity; Reward devaluation.

MeSH terms

  • Adolescent
  • Adult
  • Anhedonia / physiology
  • Anxiety Disorders / psychology
  • Anxiety* / psychology
  • Depression* / psychology
  • Depressive Disorder / psychology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Self Report
  • Young Adult