Recent advances and applications of the CRISPR-Cas system in the gene therapy of blood disorders

Gene. 2024 Dec 30:931:148865. doi: 10.1016/j.gene.2024.148865. Epub 2024 Aug 20.

¹ Stem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran; Research Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran. Electronic address: [email protected].
² Stem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran.
³ Department of Hematology and Medical Laboratory Sciences, Faculty of Allied Medicine, Kerman University of Medical Sciences, Kerman, Iran.
⁴ Stem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran; Department of Hematology and Medical Laboratory Sciences, Faculty of Allied Medicine, Kerman University of Medical Sciences, Kerman, Iran.
⁵ Research Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.

No abstract available

Keywords: Blood disorders; CRISPR-Cas; Clinical trials; Delivery methods; Gene therapy.

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