Hepatitis B Virus Treatment in Children: Common Challenges and Management Options in a Case-Based Format

J Pediatric Infect Dis Soc. 2024 Nov 21;13(Supplement_5):S142-S147. doi: 10.1093/jpids/piae084.

Abstract

The management of hepatitis B virus (HBV) in pediatrics presents many challenges, given the potential sequelae of untreated infection including hepatic fibrosis, cirrhosis, and malignancy, and a lack of clear guidance on the timing of treatment initiation. The goal of this review is to feature common clinical scenarios that occur in the evaluation and treatment of HBV infection in children. Each vignette presents an opportunity to discuss guidelines and evidence-based practices as well as review landmark studies and evolving practices.

Keywords: children; hepatitis B virus; prevention; treatment; vaccine.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Adolescent
  • Antiviral Agents* / therapeutic use
  • Hepatitis B virus
  • Hepatitis B* / drug therapy
  • Hepatitis B, Chronic / drug therapy
  • Humans
  • Male
  • Practice Guidelines as Topic

Substances

  • Antiviral Agents