Objective assessment of the effect of surgery on limb function after medial femoral condyle free flap harvest: biomechanical parameters

Int J Oral Maxillofac Surg. 2025 Feb;54(2):123-129. doi: 10.1016/j.ijom.2024.08.028. Epub 2024 Aug 22.

Abstract

The aim of this study was to evaluate the influence of medial femoral condyle (MFC) free flap harvest on donor site muscle strength and kinematic parameters of gait. The study included 30 patients treated for head and neck squamous cell carcinoma who underwent reconstruction with an MFC free flap. In each case, the donor site was the left thigh. A dynamometer was used to measure muscle strength, in isokinetic bilateral mode and with concentric contraction for the extension/flexion knee pattern, at 18 months postoperative. In addition, kinematic data were obtained and evaluated. On statistical analysis, no significant difference in muscle strength of the quadriceps muscle was found between the left involved and right uninvolved lower extremities (P = 0.124). Also, when comparing hamstring strength, no statistically significant difference was found between the left involved and right uninvolved sides (P = 0.210). Moreover, spatiotemporal gait parameters did not differ significantly between the involved and uninvolved legs (all P > 0.05), and no differences in kinematic or kinetic parameters were observed. This study reports the effects of MFC free flap harvest on the knee muscle strength and locomotion of patients. For most biomechanical parameters investigated, there was no effect (positive or negative).

Keywords: Free tissue flaps; Head and neck neoplasms; Muscle strength; Surgical flaps; Transplant donor site.

MeSH terms

  • Adult
  • Aged
  • Biomechanical Phenomena
  • Carcinoma, Squamous Cell / surgery
  • Female
  • Femur / surgery
  • Free Tissue Flaps*
  • Gait / physiology
  • Head and Neck Neoplasms / surgery
  • Humans
  • Male
  • Middle Aged
  • Muscle Strength Dynamometer
  • Muscle Strength* / physiology
  • Plastic Surgery Procedures / methods
  • Quadriceps Muscle / physiology
  • Squamous Cell Carcinoma of Head and Neck / surgery
  • Treatment Outcome