Ṯābit Ibn Qurrah's contributions to toxicology

Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug 23. doi: 10.1007/s00210-024-03374-3. Online ahead of print.

Abstract

Mankind has been familiar with poisons since ancient times. On the other hand, there is a wealth of knowledge in the medical books including medieval works of Middle Eastern polymaths such as Avicenna, "al-Rāzī," and "Ṯābit Ibn Qurrah." This study presented and analyzed the knowledge of medical toxicology in one of the mainstay works of "Ṯābit Ibn Qurrah" entitled "al-Ḏaḫirah Fy Ꜥilm al-Tibb" also known as The Treasury of Medicine after the translation of the book from Arabic to English carefully and faithfully. Also, related toxicological literature was applied wherever required using English, Arabic, and Persian databases including Scopus, PubMed, Web of Science, WorldCat, Magiran, IranDoc, Scientific Information Database, Noor Mags, Noorlib, and Al Manhal. Our research revealed that chapter 25 of the mentioned book specifically focused on toxicology. This chapter was divided into sections on different aspects of toxicology from the categorization of poisons to compound mixtures causing poisonings to introducing blade poisons to signs and symptoms of poisonings, preventive approaches, and therapeutic agents. Specific antidotes and general therapies were introduced that included medicinal plants, cupping therapy, and bandages, just to name a few. Also, there were some monographs on the common poisonous agents and their treatments. The toxicological data of the book was comparable with modern toxicology. Our study highlighted the contributions of "Ṯābit Ibn Qurrah" to medical toxicology by authoring The Treasury of Medicine. Further research is recommended to elucidate the full aspects of the history of toxicology including the contributions of the past scholars.

Keywords: Antidote; History; Medicinal plants; Pharmacology; Toxicology; Traditional medicine; “Ṯābit Ibn Qurrah,” Treasury of Medicine.

Publication types

  • Review