The RNA-binding protein IGF2BP1 regulates stability of mRNA transcribed from FOXM1 target genes in hypermitotic meningiomas

Nathan K Leclair; Calixto-Hope G Lucas; Kanish Mirchia; Kathleen McCortney; Craig M Horbinski; David R Raleigh; Olga Anczukow

doi:10.1007/s00401-024-02788-w

The RNA-binding protein IGF2BP1 regulates stability of mRNA transcribed from FOXM1 target genes in hypermitotic meningiomas

Acta Neuropathol. 2024 Aug 23;148(1):28. doi: 10.1007/s00401-024-02788-w.

Authors

Nathan K Leclair¹, Calixto-Hope G Lucas^{2

3

4}, Kanish Mirchia^{5

6

7}, Kathleen McCortney⁸, Craig M Horbinski^{8

9}, David R Raleigh^{10

11

12}, Olga Anczukow^{13

14

15}

Affiliations

¹ The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
² Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.
³ Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
⁴ Department of Oncology, Johns Hopkins University, Baltimore, MD, USA.
⁵ Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
⁶ Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
⁷ Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
⁸ Department of Neurological Surgery, Northwestern University, Chicago, IL, USA.
⁹ Department of Pathology, Northwestern University, Chicago, IL, USA.
¹⁰ Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA. [email protected].
¹¹ Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA. [email protected].
¹² Department of Pathology, University of California San Francisco, San Francisco, CA, USA. [email protected].
¹³ The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. [email protected].
¹⁴ Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA. [email protected].
¹⁵ Institute for Systems Genomics, UConn Health, Farmington, CT, USA. [email protected].

No abstract available

Publication types

Letter

MeSH terms

Forkhead Box Protein M1* / genetics
Forkhead Box Protein M1* / metabolism
Gene Expression Regulation, Neoplastic
Humans
Meningeal Neoplasms* / genetics
Meningeal Neoplasms* / metabolism
Meningeal Neoplasms* / pathology
Meningioma* / genetics
Meningioma* / metabolism
Meningioma* / pathology
RNA Stability / genetics
RNA, Messenger* / genetics
RNA, Messenger* / metabolism
RNA-Binding Proteins* / genetics
RNA-Binding Proteins* / metabolism

Substances

RNA-Binding Proteins
RNA, Messenger
Forkhead Box Protein M1
IGF2BP1 protein, human
FOXM1 protein, human

Publication types

MeSH terms

Substances

Grants and funding