Response by Shridhar et al to Letter Regarding Article, "MDM2 Regulation of HIF Signaling Causes Microvascular Dysfunction in Hypertrophic Cardiomyopathy"

Circulation. 2024 Aug 27;150(9):e201-e202. doi: 10.1161/CIRCULATIONAHA.124.069703. Epub 2024 Aug 26.

Authors

Puneeth Shridhar^{1

2}, Soumojit Pal¹, Nicolas G Clavere¹, Jason R Becker^{1

2}

Affiliations

¹ Division of Cardiology, Department of Medicine and Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, PA (P.S., S.P., N.G.C., J.R.B.).
² Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, PA (P.S., J.R.B.).

PMID: 39186528
DOI: 10.1161/CIRCULATIONAHA.124.069703

No abstract available

Publication types

Letter

MeSH terms

Animals
Cardiomyopathy, Hypertrophic* / metabolism
Cardiomyopathy, Hypertrophic* / physiopathology
Humans
Hypoxia-Inducible Factor 1, alpha Subunit / genetics
Hypoxia-Inducible Factor 1, alpha Subunit / metabolism
Microcirculation
Microvessels / metabolism
Microvessels / physiopathology
Proto-Oncogene Proteins c-mdm2* / genetics
Proto-Oncogene Proteins c-mdm2* / metabolism
Signal Transduction*

Substances

Proto-Oncogene Proteins c-mdm2
Hypoxia-Inducible Factor 1, alpha Subunit