Paternal Valproate Treatment and Risk of Childhood Neurodevelopmental Disorders: Precautionary Regulatory Measures Are Insufficiently Substantiated

Affiliations

• ¹ Reproductive Toxicology Center, A Non-Profit Foundation, Washington, DC, USA.
• ² Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
• ³ Department of Clinical Pharmacology, Odense University Hospital, Odense, Denmark.
• ⁴ Division of Medical Genetics, Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
• ⁵ Regional Center of Pharmacovigilance, Department of Pharmacology, Cochin Port Royal Hospital, APHP, Paris, France.
• ⁶ The Rotunda Hospital, Dublin, Ireland.
• ⁷ School of Pharmacy and Biomedical Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
• ⁸ Department of Psychiatry and Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
• ⁹ Division of Clinical Genetics, Munroe Meyer Institute, University of Nebraska Medical Center, Omaha, Nebraska, USA.
• ¹⁰ The Israeli Teratology Information Service, Ministry of Health, Jerusalem, Israel.
• ¹¹ The Hebrew University Hadassah Medical School, Jerusalem, Israel.
• ¹² Department of Internal Medicine, Northeast Ohio Medical University, Rootstown, Ohio, USA.
• ¹³ Department of Paediatrics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
• ¹⁴ UK Teratology Information Service, Newcastle upon Tyne, UK.
• ¹⁵ Royal Hospital for Women, Randwick, New South Wales, Australia.
• ¹⁶ Center for Epidemiology and Maternal-Child Health (CEOH), Washington, DC, USA.
• ¹⁷ MotherToBaby Connecticut, Division of Medical Genetics, UConn Health, Farmington, Connecticut, USA.
• ¹⁸ Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
• ¹⁹ Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
• ²⁰ Service of Pharmacy, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
• ²¹ Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.
• ²² MotherToBaby Utah, Utah Department of Health, Salt Lake City, Utah, USA.
• ²³ Charité - Universitätsmedizin Berlin, Pharmakovigilanzzentrum Embryonaltoxikologie, Institut für Klinische Pharmakologie und Toxikologie, Berlin, Germany.