Reactive oxygen species in cardiac electrophysiology: loss of Scn1b increases susceptibility to oxidative stress and drives a proarrhythmic phenotype

Am J Physiol Heart Circ Physiol. 2024 Oct 1;327(4):H824-H825. doi: 10.1152/ajpheart.00568.2024. Epub 2024 Aug 30.
No abstract available

Keywords: Scn1b; reactive oxygen species; voltage-gated sodium channels.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Action Potentials
  • Animals
  • Arrhythmias, Cardiac / genetics
  • Arrhythmias, Cardiac / metabolism
  • Arrhythmias, Cardiac / physiopathology
  • Humans
  • Mice
  • Mice, Knockout
  • Myocytes, Cardiac / metabolism
  • Oxidative Stress*
  • Phenotype*
  • Reactive Oxygen Species* / metabolism

Substances

  • Reactive Oxygen Species