Hodgkin/Reed-Sternberg cells induce GPNMB expression and release from macrophages to suppress T-cell responses to the Epstein-Barr virus-encoded LMP2A protein

Affiliations

• ¹ Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham.
• ² Institute of Cancer and Genomic Sciences, University of Birmingham.
• ³ Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham.
• ⁴ Limerick Digital Cancer Research Centre, Bernal Institute and Health Research Institute and School of Medicine, University of Limerick, Limerick.
• ⁵ Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom; The Palatine Centre, Durham University, Durham.
• ⁶ Department of Pediatrics, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc, Czech Republic.
• ⁷ University Hospitals Plymouth NHS Trust, Plymouth.
• ⁸ Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre University of Birmingham, Birmingham.
• ⁹ Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom; Royal College of Surgeons in Ireland Medical University of Bahrain, Manama, PO Box 15503, Bahrain. [email protected].
• ¹⁰ Limerick Digital Cancer Research Centre, Bernal Institute and Health Research Institute and School of Medicine, University of Limerick, Limerick, Ireland; Royal College of Surgeons in Ireland Medical University of Bahrain, Manama, Bahrain; Department of Clinical and Molecular Pathology, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc. [email protected].