Methotrexate prolonged the shedding of replicable SARS-CoV-2 with re-increased antigens in a rheumatoid arthritis patient

Affiliations

• ¹ Rheumatic Disease Center, Sasebo Chuo Hospital, Sasebo, Japan.
• ² Department of Respiratory Medicine, Sasebo Chuo Hospital, Sasebo, Japan.
• ³ Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
• ⁴ Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
• ⁵ Department of Virology, Institute of Tropical Medicine, Dejima Infectious Disease Research Alliance, Nagasaki University, Nagasaki, Japan.