Bioaccumulation and biotransformation of selenium nanoparticles in soybean and natto, and the bioaccessibility of multi-elements and amino acids

Bingjie Zhao; Sasa Zhang; Kui Li; Yanbin Guo

doi:10.1016/j.foodchem.2024.141034

Bioaccumulation and biotransformation of selenium nanoparticles in soybean and natto, and the bioaccessibility of multi-elements and amino acids

Food Chem. 2025 Jan 15;463(Pt 1):141034. doi: 10.1016/j.foodchem.2024.141034. Epub 2024 Aug 30.

Authors

Bingjie Zhao¹, Sasa Zhang¹, Kui Li¹, Yanbin Guo²

Affiliations

¹ College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China; Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, Beijing 100193, China.
² College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China; Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, Beijing 100193, China. Electronic address: [email protected].

PMID: 39236391
DOI: 10.1016/j.foodchem.2024.141034

Abstract

Soybean is a food crop with strong selenium (Se) enrichment ability. Selenium nanoparticles (SeNPs) are a low-toxic Se source. To develop strategies in SeNPs biofortification of soybean and natto, the effects of Se enrichment and natto fermentation on selenoamino acids, mineral elements, free amino acids, γ-polyglutamic acid, nattokinase, and bioaccessibility were investigated. Soybean grains were able to convert SeNPs into selenomethionine (SeMet). Selenium enrichment and natto fermentation influenced the enrichment and distribution of multi-elements in soybean, as well as the composition of free and bound amino acids. Selenium enrichment had no significant effect on the bioaccessibility of amino acids. After natto fermentation, the bioaccessibility of SeMet, Fe, Mn, Cu, and Zn in the gastrointestinal tract increased significantly by 10.1-18.9 %. These findings indicate that SeNPs can enhance the Se content of soybean grains, and natto fermentation can further improve the nutritional quality of Se-enriched soybean.

Keywords: Free amino acids; Multi-elements distribution; Selenomethionine; Soybean grains; γ-Polyglutamic acid.

MeSH terms

Amino Acids* / analysis
Amino Acids* / chemistry
Amino Acids* / metabolism
Bioaccumulation
Biological Availability
Biotransformation
Fermentation
Glycine max* / chemistry
Glycine max* / metabolism
Humans
Nanoparticles* / chemistry
Nanoparticles* / metabolism
Selenium* / analysis
Selenium* / chemistry
Selenium* / metabolism

Substances

Selenium
Amino Acids