Combination of acute diabetic neuropathies following intensive glycaemic management

Pract Neurol. 2025 Jan 16;25(1):51-55. doi: 10.1136/pn-2024-004262.

Abstract

While acute and monophasic diabetic neuropathy variants are considered relatively uncommon, diabetes mellitus affects over 6% of the global population, with more than 50% experiencing some form of diabetic neuropathy. Treatment-induced neuropathy of diabetes is an iatrogenic, transient neuropathy characterised by small fibre involvement precipitated by rapid glycaemic control. Diabetic lumbosacral radiculoplexus neuropathy is an asymmetric, predominantly motor neuropathy of the lower limbs, typically starting with localised leg pain. We present a 59-year-old man manifesting features of both conditions following a 12.5% decrease in glycated haemoglobin over 3 months.

Keywords: DIABETES MELLITUS; DIABETIC NEUROPATHY; NEUROMUSCULAR.

Publication types

  • Case Reports

MeSH terms

  • Diabetic Neuropathies*
  • Glycated Hemoglobin / analysis
  • Glycated Hemoglobin / metabolism
  • Glycemic Control
  • Humans
  • Male
  • Middle Aged

Substances

  • Glycated Hemoglobin