Evaluation of the ability of laboratory, ultrasonography, and Doppler ultrasonography findings to distinguish between simple and complicated appendicitis

J Clin Ultrasound. 2024 Nov-Dec;52(9):1394-1401. doi: 10.1002/jcu.23811. Epub 2024 Sep 6.

Abstract

Objective: To evaluate the utility of laboratory ultrasonographic and Doppler ultrasonographic findings in the differentiation of simple and complicated appendicitis.

Methods: A prospective study was conducted, including pediatric patients who underwent surgery with the diagnosis of appendicitis.

Results: Fifty patients, who were found to have appendicitis on ultrasonographic examination, were included. The mean age was found to be 12.80 ± 3.67 years, with 30% female and 70% male. The patients were histopathologically divided into two groups: simple appendicitis (Group 1, 41 patients, 82%) and complicated appendicitis (Group 2, 9 patients, 18%). CRP (C-reactive protein) levels (p = 0.004) and periappendiceal fatty tissue thickness (PFI) (p < 0.005) were found to be statistically significantly higher in Group 2 compared to Group 1. The portal vein (PV) diameter and peak systolic velocity (PSV) values were significantly higher in the study group compared to the control group (p = 0.033, p = 0.001).

Conclusion: Doppler ultrasonographic examination did not significantly differentiate complicated from simple appendicitis. The CRP value is an independent risk factor in the diagnosis of complicated appendicitis, and the presence of a significant increase in mesenteric tissue thickness is one of the important criteria for differentiating complicated appendicitis from simple appendicitis.

Keywords: CRP; Doppler ultrasound; appendicitis; child; ultrasound.

MeSH terms

  • Adolescent
  • Appendicitis* / diagnostic imaging
  • Appendix / diagnostic imaging
  • C-Reactive Protein / analysis
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Reproducibility of Results
  • Ultrasonography / methods
  • Ultrasonography, Doppler* / methods

Substances

  • C-Reactive Protein