Coronary drug-coated balloons: A comprehensive review of clinical applications and controversies

Muzamil Khawaja; Michael Britt; Affan Rizwan; Jocelyn Abraham; Taylor Nguyen; Uzair Munaf; Muhammad Asad Khan; Hassaan Arshad; Muhamed Munye; Noah Newman; Alfonso Ielasi; Simon Eccleshall; Vassilios S Vassiliou; Ioannis Merinopoulos; Bernardo Cortese; Chayakrit Krittanawong

doi:10.1016/j.tcm.2024.08.006

Coronary drug-coated balloons: A comprehensive review of clinical applications and controversies

Trends Cardiovasc Med. 2024 Sep 5:S1050-1738(24)00079-3. doi: 10.1016/j.tcm.2024.08.006. Online ahead of print.

Authors

Muzamil Khawaja¹, Michael Britt², Affan Rizwan³, Jocelyn Abraham⁴, Taylor Nguyen⁵, Uzair Munaf⁶, Muhammad Asad Khan⁷, Hassaan Arshad⁸, Muhamed Munye⁹, Noah Newman⁹, Alfonso Ielasi¹⁰, Simon Eccleshall¹¹, Vassilios S Vassiliou¹², Ioannis Merinopoulos¹², Bernardo Cortese¹³, Chayakrit Krittanawong¹⁴

Affiliations

¹ Department of Cardiology, Emory University School of Medicine, Atlanta, GA 30322, USA.
² Department of Internal Medicine, Emory University, Atlanta, GA 30322, USA.
³ Department of Internal Medicine, The University of Mississippi Medical Center, Jackson, MS 39216, USA.
⁴ Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 USA.
⁵ Division of Hospital Medicine, Northwestern Memorial Hospital, Chicago, IL 60611, United States.
⁶ Department of Internal Medicine, Dow Medical College, 75300 Karachi, Pakistan.
⁷ Department of Family Medicine, West Chicago Immediate Care, West Chicago, IL 60185-2847, USA.
⁸ Department of Internal Medicine, Capital Health Regional Medical Centre, Trenton, NJ 08638-4143, USA.
⁹ Department of Internal Medicine, Emory University, Atlanta, GA, 30322, USA.
¹⁰ U.O. Cardiologia Ospedaliera, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
¹¹ Department of Cardiology, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, United Kingdom.
¹² Department of Cardiology, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, United Kingdom; Norfolk and Norwich University Hospital NHS Foundation Trust and University of East Anglia, Norwich, England.
¹³ Harrington Heart & Vascular Institute, University Hospitals, Cleveland, Ohio, USA; Fondazione Ricerca e Innovazione Cardiovascolare, Milano, Italy; DCB Academy, Milano, Italy.
¹⁴ Department of Cardiology, NYU Langone Health and NYU School of Medicine, New York, NY 10016, USA. Electronic address: [email protected].

PMID: 39243831
DOI: 10.1016/j.tcm.2024.08.006

Abstract

Drug-coated balloons have emerged as a promising therapeutic option in the treatment of cardiovascular disease. This review article provides an overview of the concept of drug-coated balloons and their clinical applications in both de novo and treated coronary artery disease. A summary of key clinical trials and registry studies evaluating drug-coated balloons is presented for reference. Overall, this article aims to provide clinicians and researchers with a comprehensive understanding of the current state of drug-coated balloon technology and its implications in clinical practice.

Keywords: AMI; CAD; CTO; Coronary Drug-Coated Balloons; DCB.

Publication types

Review