Left ventricular thrombus in patient with nonischemic cardiomyopathy: A case report

Radiol Case Rep. 2024 Aug 24;19(11):5241-5247. doi: 10.1016/j.radcr.2024.07.179. eCollection 2024 Nov.

Abstract

Left ventricular thrombus (LVT) is a severe consequence that typically follows acute myocardial infarction (MI) and can occur in nonischemic cardiomyopathies. In patients who have experienced an ST-segment elevation acute myocardial infarction (STEMI), LVT is seen up to 15% of the time; for patients without an ischemic cardiomyopathy, it is only 2% to 36% of the time. According to Virchow's triad, the cornerstone of LVT formation includes endothelial injury, blood stasis, and hypercoagulability. However, LVT increases morbidity and mortality in patients with both ischemic and nonischemic cardiomyopathies by increasing the risk of stroke or systemic embolism. Studies on nonischemic etiology are limited, and the majority of LVT case series concentrate on ischemic cardiomyopathies. We present this case with the nonischemic cardiomyopathies caused by LVT. Specifically, the patient underwent coronary artery assessment using photon-counting computed tomography, which is among the most advanced systems worldwide.

Keywords: Dilated cardiomyopathy; Glomerulonephritis; Left ventricular thrombus; Nonischemic cardiomyopathies; Photon-counting computed tomography.

Publication types

  • Case Reports