Very rare tumor of the nasal cavity, hamartome adenomatoid respiratory epithelial chondro-osseous (COREAH): About a case

Introduction and importance: Chondroosseous respiratory adenomatous epithelial hamartoma (COREAH) is a rare benign lesion of the nose and sinuses, with some cases reported in the literature.

Clinical case: We present here a case of COREAH, in a woman whose clinical examination finds a polypoid mass in the left nasal cavity. Computed tomography (CT) and magnetic resonance imaging (MRI) confirmed the presence of a large mass in the anterior nasal cavity extended to the cranial cavity through the screened blade on the right side. The mass was completely resected by endoscopy. Histological examination confirmed the nature of the mass as COREAH. A hamartoma can be considered a proliferation of endogenous cells or tissues at this anatomical site.

Clinical discussion: Several hamartomatous lesions have been recognized in the sinonasal region. The majority are mesenchymal, most often vascular lesions. Pure chondromatous hamartomas of the nasal cavity, although rare, also occur.

Conclusion: COREAH is a benign hamartomatous proliferation of the respiratory epithelium, submucosal glands and chondroosseous mesenchyma. Differential clinical diagnoses include benign and malignant tumors of the nasal cavity and sinuses. Properly recognizing this lesion as radiologically benign is essential to avoid radical surgery.