Acute lung pathology in the immunocompromised child

Pediatr Radiol. 2024 Sep 13. doi: 10.1007/s00247-024-06047-8. Online ahead of print.

Abstract

Children with compromised immune systems, whether due to primary or secondary immunodeficiencies, are susceptible to a broad spectrum of acute intrathoracic pathologies. These include infections, pulmonary edema, and malignancies. Pulmonary issues are common and perilous in this population, necessitating prompt and precise diagnosis for effective management. This review aims to provide an overview of such conditions, focusing on the imaging appearances of the most prevalent acute lung conditions affecting immunocompromised children. It emphasizes the critical importance of an integrated clinical and radiological approach when diagnosing these acute pulmonary disease states.

Keywords: Child; Computerized tomography; Immunosuppression; Infection; Lung; Neoplasm.