Postmortem Detection of "Clinically Undiagnosed" Diffuse Large B-Cell Lymphoma: Gross and Microscopic Findings

Diagnostics (Basel). 2024 Aug 29;14(17):1901. doi: 10.3390/diagnostics14171901.

Abstract

Diffuse large B-cell lymphoma is considered the most found non-Hodgkin lymphoma in adults. Diffuse large B-cell lymphoma, which also occurs in sporadic forms, is associated with some pathological conditions, including human immunodeficiency virus infection, especially if it progresses to AIDS. The authors report the case of a 45-year-old man with AIDS in whom a postmortem diagnosis of diffuse large B-cell lymphoma was performed. The proposed images document extensive pluri-visceral involvement, already visible macroscopically, and subsequently confirmed through histological examination.

Keywords: AIDS; forensic autopsy; forensic pathology; large B-cell lymphoma; postmortem diagnosis.

Grants and funding

This research received no external funding.