Ranolazine Unveiled: Rediscovering an Old Solution in a New Light

J Clin Med. 2024 Aug 23;13(17):4985. doi: 10.3390/jcm13174985.

Abstract

Ranolazine is an anti-anginal medication that has demonstrated antiarrhythmic properties by inhibiting both late sodium and potassium currents. Studies have shown promising results for ranolazine in treating both atrial fibrillation and ventricular arrhythmias, particularly when used in combination with other medications. This review explores ranolazine's mechanisms of action and its potential role in cardiac arrhythmias treatment in light of previous clinical studies.

Keywords: arrhythmias; atrial fibrillation; ranolazine; sodium current inhibition; ventricular arrhythmias.

Publication types

  • Review

Grants and funding

This research received no external funding.