Demographic and clinical characteristics of individuals with psychosis symptoms who died by suicide: Findings of a psychological autopsy study

Psychiatry Res. 2024 Dec:342:116185. doi: 10.1016/j.psychres.2024.116185. Epub 2024 Sep 10.

Abstract

Suicide is a critical public health concern among individuals with schizophrenia spectrum disorders (SSDs). Still, significant gaps remain in understanding relationships between suicide outcomes and both demographic and clinical characteristics. Data were examined from 57 adults of a psychological autopsy study who had psychosis symptoms and died between 1989 and 2017 in the Midwestern United States. This study compared demographic and clinical characteristics of those who died by suicide (n = 26) to those who died by natural (n = 26) or accidental (n = 5) causes. Those who died by suicide were more often younger, white/Caucasian, more educated, and more often employed than those who died by natural or accidental causes (p < .05). Furthermore, symptoms of depression, recurrent suicidal ideation, history of suicide attempt, and being in a first episode of psychosis were experienced significantly more by those who died by suicide in comparison to natural or accidental causes (p < .05). Findings highlight the need to consider depression in suicide risk for psychosis populations, intervene in early stages of psychosis illness, and implement suicide prevention strategies tailored to individuals with psychosis and SSDs. Implications point towards the need for tailored interventions to mitigate risk for suicide death in this vulnerable population.

Keywords: Depression; First episode; Psychological autopsy; Psychosis; Suicide.

MeSH terms

  • Adult
  • Aged
  • Depression / epidemiology
  • Depression / psychology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Midwestern United States / epidemiology
  • Psychotic Disorders* / epidemiology
  • Psychotic Disorders* / psychology
  • Schizophrenia / epidemiology
  • Suicidal Ideation
  • Suicide* / psychology
  • Suicide* / statistics & numerical data
  • Suicide, Attempted / psychology
  • Suicide, Attempted / statistics & numerical data
  • Young Adult