Identification of the novel HLA-B*56:100 allele by next-generation sequencing

HLA. 2024 Sep;104(3):e15691. doi: 10.1111/tan.15691.

Abstract

HLA-B*56:100 differs from HLA-B*56:20:02 by one nucleotide substitution at codon 147.2 in exon 3.

Keywords: HLA; HLA‐B*56:100; new allele; next generation sequencing.

MeSH terms

  • Alleles*
  • Base Sequence
  • Codon
  • Exons*
  • HLA-B Antigens* / genetics
  • High-Throughput Nucleotide Sequencing* / methods
  • Histocompatibility Testing* / methods
  • Humans
  • Polymorphism, Single Nucleotide
  • Sequence Alignment
  • Sequence Analysis, DNA / methods

Substances

  • HLA-B Antigens
  • Codon