Corneal biomechanics in patients with allergic conjunctivitis

Indian J Ophthalmol. 2024 Nov 1;72(Suppl 5):S728-S733. doi: 10.4103/IJO.IJO_654_24. Epub 2024 Sep 19.

Abstract

Allergic conjunctivitis (AC) comprises a group of conditions triggered by environmental allergens, substantially diminishing the quality of life, particularly among children and adolescents. The mechanical impact of eye rubbing in patients with AC is known to induce biomechanical alterations in the cornea. Modern instruments enable the detection and quantification of these corneal biomechanical changes. The ocular response analyzer and CorVis ST have become standard tools for assessing corneal biomechanical properties. We conducted a review of studies that have investigated corneal biomechanics in patients with AC using both devices to elucidate the association between corneal biomechanical changes and early ectasia development. Our analysis highlights significant findings regarding the tomographic biomechanical index parameter in corneal biomechanics among patients with AC. These findings underscore the importance of ocular screening for all patients to promptly detect subclinical keratoconus changes, thereby improving disease management and outcomes.

Publication types

  • Review

MeSH terms

  • Biomechanical Phenomena
  • Conjunctivitis, Allergic* / diagnosis
  • Conjunctivitis, Allergic* / physiopathology
  • Cornea* / diagnostic imaging
  • Cornea* / physiopathology
  • Corneal Topography / methods
  • Elasticity / physiology
  • Humans
  • Keratoconus / diagnosis
  • Keratoconus / physiopathology