Infarct Size Reduction With Cyclosporine A in Circulatory Death Rat Hearts: Reducing Effective Ischemia Time With Therapy During Reperfusion

Circ Heart Fail. 2024 Oct;17(10):e011846. doi: 10.1161/CIRCHEARTFAILURE.124.011846. Epub 2024 Sep 20.
No abstract available

Keywords: calcium; cyclosporine; mitochondrial permeability transition pore; reperfusion injury; warm ischemia.

Publication types

  • Letter

MeSH terms

  • Animals
  • Cyclosporine* / therapeutic use
  • Disease Models, Animal
  • Male
  • Myocardial Infarction* / drug therapy
  • Myocardial Infarction* / physiopathology
  • Myocardial Reperfusion / methods
  • Myocardial Reperfusion Injury* / physiopathology
  • Myocardial Reperfusion Injury* / prevention & control
  • Myocardium / metabolism
  • Myocardium / pathology
  • Rats
  • Time Factors

Substances

  • Cyclosporine