Comments and illustrations of the European Federation of Societies for Ultrasound in Medicine contrast-enhanced ultrasound guidelines. Rare pancreatic tumors, imaging features on transabdominal ultrasound and EUS with contrast enhancement: Rare epithelial pancreatic tumors: solid pseudopapillary neoplasm, acinar cell carcinoma, mixed neuroendocrine-non-neuroendocrine neoplasms, some rare subtypes of pancreatic adenocarcinoma and pancreatoblastoma

Kathleen Möller; Axel Löwe; Christian Jenssen; Manoop S Bhutani; Wei On; Simon M Everett; Barbara Braden; Michael Hocke; Andrew Healey; Yi Dong; Michael Gerber; Siegbert Faiss; Mihai Rimbas; Nan Ge; Siyu Sun; Heike Taut; David Srivastava; Eike Burmester; Christoph F Dietrich

doi:10.1097/eus.0000000000000056

Comments and illustrations of the European Federation of Societies for Ultrasound in Medicine contrast-enhanced ultrasound guidelines. Rare pancreatic tumors, imaging features on transabdominal ultrasound and EUS with contrast enhancement: Rare epithelial pancreatic tumors: solid pseudopapillary neoplasm, acinar cell carcinoma, mixed neuroendocrine-non-neuroendocrine neoplasms, some rare subtypes of pancreatic adenocarcinoma and pancreatoblastoma

Endosc Ultrasound. 2024 May-Jun;13(3):129-144. doi: 10.1097/eus.0000000000000056. Epub 2024 Apr 30.

Authors

Kathleen Möller¹, Axel Löwe², Christian Jenssen^{3

4}, Manoop S Bhutani⁵, Wei On⁶, Simon M Everett⁶, Barbara Braden⁷, Michael Hocke⁸, Andrew Healey⁹, Yi Dong¹⁰, Michael Gerber¹, Siegbert Faiss¹, Mihai Rimbas¹¹, Nan Ge¹², Siyu Sun¹², Heike Taut¹³, David Srivastava^{2

14}, Eike Burmester¹⁵, Christoph F Dietrich²

Affiliations

¹ Medical Department I/Gastroenterology, Sana Hospital Lichtenberg, Berlin, Germany.
² Department Allgemeine Innere Medizin der Kliniken (DAIM) Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland.
³ Department of Internal Medicine, Krankenhaus Märkisch-Oderland, Strausberg, Germany.
⁴ Brandenburg Institute for Clinical Ultrasound (BICUS) at Medical University Brandenburg, Neuruppin, Germany.
⁵ Department of Gastroenterology, Hepatology and Nutrition, UT MD Anderson Cancer Center, Houston, Texas, USA.
⁶ Department of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
⁷ Translational Gastroenterology Unit, Oxford University Hospitals, Oxford, United Kingdom.
⁸ Medical Department, Helios Klinikum Meiningen, Germany.
⁹ Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
¹⁰ Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
¹¹ Department of Gastroenterology, Clinic of Internal Medicine, Colentina Clinical Hospital, Carol Davila University of Medicine, Bucharest, Romania.
¹² Department of Endoscopy Center, Shengjing Hospital of China Medical University, Liaoning Province, China.
¹³ Children's Hospital, Universitätsklinikum Dresden, Technische Universität Dresden, Dresden, Germany.
¹⁴ University Hospital, Inselspital Bern, Switzerland.
¹⁵ Medizinische Klinik I, Sana Kliniken Luebeck, Lübeck, Germany.

Abstract

Rare malignant pancreatic lesions are systematically reported in this review. The focus is on the imaging appearance of the rare epithelial pancreatic tumors such as the solid pseudopapillary neoplasm, acinar cell carcinoma, rare subtypes of adenocarcinoma, and pancreatoblastoma as seen on ultrasound, EUS, and contrast-enhanced ultrasound or EUS. The present overview summarizes the data and shows that not every pancreatic tumor is likely to be the most common entities of ductal adenocarcinoma or neuroendocrine tumor.

Keywords: Acinar cell carcinoma; Contrast-enhanced EUS; Contrast-enhanced US; EUS; Imaging; Rare subtypes of pancreatic adenocarcinoma; Solid pseudopapillary tumor; US; Ultrasound.