MR Imaging-Guided Focused Ultrasound for Breast Tumors

Matthew DeWitt; Zehra E F Demir; Thomas Sherlock; David R Brenin; Natasha D Sheybani

doi:10.1016/j.mric.2024.04.004

MR Imaging-Guided Focused Ultrasound for Breast Tumors

Magn Reson Imaging Clin N Am. 2024 Nov;32(4):593-613. doi: 10.1016/j.mric.2024.04.004. Epub 2024 May 16.

Authors

Matthew DeWitt¹, Zehra E F Demir², Thomas Sherlock², David R Brenin³, Natasha D Sheybani⁴

Affiliations

¹ Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA; Focused Ultrasound Cancer Immunotherapy Center, University of Virginia, Charlottesville, VA, USA.
² Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
³ Focused Ultrasound Cancer Immunotherapy Center, University of Virginia, Charlottesville, VA, USA; Division of Surgical Oncology, University of Virginia Health System, Charlottesville, VA, USA.
⁴ Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA; Focused Ultrasound Cancer Immunotherapy Center, University of Virginia, Charlottesville, VA, USA; Department of Radiology & Medical Imaging, University of Virginia, Charlottesville, VA, USA. Electronic address: [email protected].

PMID: 39322350
DOI: 10.1016/j.mric.2024.04.004

Abstract

Breast tumors remain a complex and prevalent health burden impacting millions of individuals worldwide. Challenges in treatment arise from the invasive nature of traditional surgery and, in malignancies, the complexity of treating metastatic disease. The development of noninvasive treatment alternatives is critical for improving patient outcomes and quality of life. This review aims to explore the advancements and applications of focused ultrasound (FUS) technology over the past 2 decades. FUS offers a promising noninvasive, nonionizing intervention strategy in breast tumors including primary breast cancer, fibroadenomas, and metastatic breast cancer.

Keywords: Ablation; Breast tumors; Cancer; Fibroadenoma; Focused ultrasound; MR imaging; Metastasis.

Publication types

Review

MeSH terms

Breast / diagnostic imaging
Breast Neoplasms* / diagnostic imaging
Female
High-Intensity Focused Ultrasound Ablation / methods
Humans
Magnetic Resonance Imaging / methods
Magnetic Resonance Imaging, Interventional* / methods
Ultrasonography, Interventional / methods