Emerging Monkeypox Virus Sublineage C.1 Causing Community Transmission, Vietnam, 2023

Emerg Infect Dis. 2024 Nov;30(11):2385-2390. doi: 10.3201/eid3011.240729. Epub 2024 Sep 25.

Abstract

We studied a community cluster of 25 mpox cases in Vietnam caused by emerging monkeypox virus sublineage C.1 and imported into Vietnam through 2 independent events; 1 major cluster carried a novel APOBEC3-like mutation. Three patients died; all had advanced HIV co-infection. Viral evolution and its potential consequences should be closely monitored.

Keywords: HIV co-infection; Vietnam; genetic changes; monkeypox virus; mpox; sexually transmitted infections; sublinear C1; viruses.

Publication types

  • Historical Article

MeSH terms

  • Adult
  • Coinfection / virology
  • Communicable Diseases, Emerging / epidemiology
  • Communicable Diseases, Emerging / transmission
  • Communicable Diseases, Emerging / virology
  • Female
  • HIV Infections / epidemiology
  • HIV Infections / transmission
  • HIV Infections / virology
  • History, 21st Century
  • Humans
  • Male
  • Middle Aged
  • Monkeypox virus* / classification
  • Monkeypox virus* / genetics
  • Mpox (monkeypox)* / epidemiology
  • Mpox (monkeypox)* / transmission
  • Mpox (monkeypox)* / virology
  • Mutation
  • Phylogeny*
  • Vietnam / epidemiology