Fall assessment in healthy older adults: Approach using rambling-trembling decomposition method

Background: This study explored useful indices of potential fall risk in healthy older adults based on comprehensive clinical and simple quantitative posturographic measurements.

Methods: A total of 64 community-dwelling older adults aged ≥65 years were classified into fallers and non-fallers based on previous fall history. After excluding two participants due to missing data, 16 and 46 participants were included in the faller and non-faller groups, respectively. We conducted major clinical measurements, including timed up and go test, 10-m walk test, functional reach test, one-leg stand test, isometric muscle strength tests, open-close stepping test, and sit-to-stand test. For quantitative posturographic measurements, participants performed standing tasks with their eyes open and closed. In the standing tasks, the time series of the center of pressure in the anteroposterior and mediolateral directions were measured and decomposed into rambling and trembling components to evaluate postural control in detail, separately. The mean velocity and root mean square of the center of pressure, rambling, and trembling were calculated and compared between fallers and non-fallers.

Findings: A significant fall-related difference was found only in the mean velocity of the rambling in the anteroposterior direction; fallers displayed greater values than non-fallers, especially while standing with their eyes closed.

Interpretation: The clinical measures failed to distinguish differences in fall risk, whereas the rambling component in the anteroposterior direction could detect substantial differences. The mean velocity of the rambling component could be useful as a sensitive screening biomarker for potential fall risks in healthy older adults.