Ethanolic extraction and GC-MS analysis of antioxidant and anticancer bioactive compounds from Mentha arvensis and Aegle marmelos

Nat Prod Res. 2024 Sep 27:1-7. doi: 10.1080/14786419.2024.2406993. Online ahead of print.

Abstract

Bioactive components used to treat human ailments are abundant in medicinal plants. Mentha arvensis and Aegle marmelos have therapeutic properties due to the presence of many phytonutrients. Gas chromatography-mass spectrometry (GC-MS) was used to evaluate the properties of the antioxidant and anticancer bioactive components found in the ethanolic extracts of Mentha arvensis and Aegle marmelos leaves. The major constituents identified in the leaf extracts were octadecanoic acid, heptadecanoic acid, 15-methyl-9,12,15-octadecatrienoic acid, ethyl ester, hexadecanoic acid, neophytadiene, pentadecane, hexadecane, and 1-octadecanol. Some of these components have antibacterial, antioxidant, anticancer, and anti-inflammatory properties. Among the identified compounds, octadecanoic acid and n-hexadecanoic acid are pivotal for their anticancer and antioxidant effects. The GC-MS characterisation indicated the existence of abundant bioactive compounds, confirming their potential therapeutic activities. This study showed that the leaves of Mentha arvensis and Aegle marmelos could be used as novel sources of antioxidants and anticancer medicines.

Keywords: Aegle marmelos; GC–MS; Mentha arvensis; anticancer; antioxidants; bioactive.