[Licorice consumption can be life-threatening]

Laeknabladid. 2024 Oct;110(10):464-468. doi: 10.17992/lbl.2024.09.809.
[Article in Icelandic]

Abstract

A 71-year-old man came to the emergency department (ED) at Landspitali University Hospital after collapsing at his home. He had a severely decreased serum potassium concentration of 2.1 mmol/L (ref. 3,5-4,8 mmol/L), along with an influenza A infection and thigh muscle weakness. Further investigations revealed atrial fibrillation, new-onset hypertension and increased urinary excretion of potassium. Serum values of aldosterone and renin were under the limit of detection. The patient had consumed a significant amount of liquorice with marzipan, over 250g per day, in the days preceding his visit to the ED. He was subsequently diagnosed with liquorice-induced hypertension and syndome of apparent mineralocordicoid excess (pseudohyperaldosteronism). This case emphasizes the need for clinicians to be aware of the dangers of liquorice consumption.

Keywords: aldosterone; gervi aldosteron heilkenni; licorice poisoning; liquorice; liquorice induced hypertension; pseudo-hyperaldosteronism.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Biomarkers / blood
  • Biomarkers / urine
  • Blood Pressure / drug effects
  • Glycyrrhiza* / adverse effects
  • Humans
  • Hypertension* / chemically induced
  • Hypertension* / diagnosis
  • Male
  • Potassium / blood
  • Risk Factors

Substances

  • Biomarkers
  • Potassium