Abstract
Twenty-six patients with metastatic pancreatic or gastric adenocarcinoma were treated with 5-fluorouracil, Adriamycin, and mitomycin C. One complete and five partial responses were observed among 15 patients with pancreatic adenocarcinoma (40% response rate) and six partial responses were observed among 11 patients with gastric adenocarcinoma (55% response rate). Responders had a significantly longer survival than nonresponders in both groups.
MeSH terms
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Adenocarcinoma / drug therapy*
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Adult
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Aged
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Antineoplastic Agents / administration & dosage*
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Clinical Trials as Topic
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Doxorubicin / administration & dosage
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Drug Therapy, Combination
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Female
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Fluorouracil / administration & dosage
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Humans
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Male
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Middle Aged
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Mitomycins / administration & dosage
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Pancreatic Neoplasms / drug therapy*
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Remission, Spontaneous
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Stomach Neoplasms / drug therapy*
Substances
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Antineoplastic Agents
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Mitomycins
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Doxorubicin
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Fluorouracil