A logic-activated nanoswitch for killing cancer cells according to assessment of drug-resistance

RSC Adv. 2024 Sep 30;14(42):31165-31169. doi: 10.1039/d4ra04651j. eCollection 2024 Sep 24.

Abstract

A logic-activated nanoswitch that could diagnose the differences between drug-resistant and non-drug-resistant cancer cells and control the release of drugs was developed for enhanced chemo-gene therapy using a standalone system. Compared to traditional treatments, the nanoswitch displayed improved anti-tumor efficiency in vitro.