Positive 68Ga-FAPI-04 PET/MRI and Negative 18F-FDG PET/CT Imaging in Incidental Appendiceal Goblet Cell Adenocarcinoma

Yu Sun; Haiyan Wang; Xing Chen; Weilun Wang; Jun Zhao

doi:10.1097/RLU.0000000000005490

Positive 68Ga-FAPI-04 PET/MRI and Negative 18F-FDG PET/CT Imaging in Incidental Appendiceal Goblet Cell Adenocarcinoma

Clin Nucl Med. 2024 Oct 2. doi: 10.1097/RLU.0000000000005490. Online ahead of print.

Authors

Yu Sun¹, Haiyan Wang, Xing Chen, Weilun Wang, Jun Zhao

Affiliation

¹ From the Department of Nuclear Medicine, Shanghai East hospital, Tongji University School of Medicine, Shanghai, China.

PMID: 39354695
DOI: 10.1097/RLU.0000000000005490

Abstract

A 70-year-old woman presented with left ovarian mass and thickened peritoneum. 18F-FDG PET/CT showed no significant FDG-avid in the whole body. 68Ga-FAPI-04 demonstrated abnormally high FAPI uptake in the ileocecal region, left ovarian lesion, and thickened peritoneum. The postoperative pathology confirmed the appendiceal goblet cell adenocarcinoma. This case highlights the superior and innovative diagnostic role of 68Ga-FAPI-04 in appendiceal goblet cell adenocarcinoma and its metastases.