Magnesium-promoted nickel-catalysed chlorination of aryl halides and triflates under mild conditions

Chem Commun (Camb). 2024 Oct 17;60(84):12213-12216. doi: 10.1039/d4cc04383a.

Abstract

In this study, we present a ligand-free nickel(II)-catalyzed halogen exchange of aromatic halides with magnesium chloride. This method effectively facilitates the retro-Finkelstein reaction for a wide range of aryl bromides, iodides and triflates, demonstrating excellent functional group tolerance. Mechanistic studies reveal that magnesium plays a crucial role in the challenging reductive elimination from Ni(II) intermediates.