Prominent Bone Marrow Infiltration in the Appendicular Skeleton in a B-cell Acute Lymphoblastic Leukemia Patient Demonstrated by FDG PET-MRI

Mengmeng Zheng; Frederick D Grant; Hongming Zhuang

doi:10.1097/RLU.0000000000005464

Prominent Bone Marrow Infiltration in the Appendicular Skeleton in a B-cell Acute Lymphoblastic Leukemia Patient Demonstrated by FDG PET-MRI

Clin Nucl Med. 2024 Dec 1;49(12):e712-e714. doi: 10.1097/RLU.0000000000005464. Epub 2024 Oct 10.

Authors

Mengmeng Zheng¹, Frederick D Grant, Hongming Zhuang

Affiliation

¹ From the Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

PMID: 39385368
DOI: 10.1097/RLU.0000000000005464

Abstract

Leukemia spread in the bone marrow typically is greater in the axial skeleton than in the appendicular skeleton. We report an unusual pattern of FDG-avid bone marrow infiltration that is more prominent in the appendicular skeleton than the axial skeleton in a pediatric patient with B-cell acute lymphoblastic leukemia.

Publication types

Case Reports

MeSH terms

Appendix / diagnostic imaging
Appendix / pathology
Bone Marrow* / diagnostic imaging
Bone Marrow* / pathology
Child
Fluorodeoxyglucose F18*
Humans
Magnetic Resonance Imaging*
Male
Multimodal Imaging
Positron-Emission Tomography*
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma* / diagnostic imaging
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma* / pathology
Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnostic imaging
Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology

Substances

Fluorodeoxyglucose F18