Unwrapping stemness to revive T cells

Science. 2024 Oct 11;386(6718):148-149. doi: 10.1126/science.ads6217. Epub 2024 Oct 10.

Authors

Carlson Tsui¹, Axel Kallies¹

Affiliation

¹ Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.

PMID: 39388579
DOI: 10.1126/science.ads6217

Abstract

Targeting epigenetic regulators prevents T cell exhaustion.

Publication types

Comment

MeSH terms

Animals
CD8-Positive T-Lymphocytes* / immunology
Epigenesis, Genetic*
Humans
Mice
T-Cell Exhaustion* / genetics