[Testosterone replacement therapy and possible side effects]

Urologie. 2024 Nov;63(11):1103-1110. doi: 10.1007/s00120-024-02455-8. Epub 2024 Oct 10.
[Article in German]

Abstract

The substitution of testosterone is basic andrological treatment. Beside the "when and how," knowledge of possible side effects is mandatory. Therefore, we highlight the effects of testosterone replacement therapy on bones, cardiac function, sexuality, gynacomatia, fertility, and contraception, but also areas of concern regarding prostate carcinoma and testosterone replacement therapy.

Der Testosteronersatz ist andrologische Basistherapie – neben wann und wie ist das Wissen um Nebenwirkungen essentiell. Vorgestellt werden Aus- und Nebenwirkungen der Testosteronsubstitution mit den Schwerpunkten: Knochenstoffwechsel, Herz, psychosexuelle Interferenzen, Gynäkomastie, Fertilität und Kontrazeption sowie das Spannungsfeld Prostatakarzinom und Testerosteronersatz.

Keywords: Bone metabolism; Cardiovascular risk; Prostate carcinoma; Sexual function; Testosterone.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Androgens / adverse effects
  • Androgens / therapeutic use
  • Female
  • Hormone Replacement Therapy* / adverse effects
  • Hormone Replacement Therapy* / methods
  • Humans
  • Hypogonadism / chemically induced
  • Hypogonadism / drug therapy
  • Male
  • Prostatic Neoplasms / drug therapy
  • Testosterone* / adverse effects
  • Testosterone* / therapeutic use

Substances

  • Testosterone
  • Androgens