Optic neuritis in Rosai Dorfman disease

Swati Phuljhele; Himani Thakur; Rohit Saxena; Rebika Dhiman; Saumyaranjan Mallick

doi:10.1038/s41433-024-03369-7

Optic neuritis in Rosai Dorfman disease

Eye (Lond). 2024 Oct 14. doi: 10.1038/s41433-024-03369-7. Online ahead of print.

Authors

Swati Phuljhele¹, Himani Thakur², Rohit Saxena², Rebika Dhiman², Saumyaranjan Mallick³

Affiliations

¹ Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India. [email protected].
² Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India.
³ Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India.

PMID: 39402165
DOI: 10.1038/s41433-024-03369-7

Abstract

A 55-year-old man while being evaluated for unexplained weight loss was found to have multiple metabolically active lymph nodes on positron emission tomography-computed tomography (PET-CT) scan, and biopsy from right axillary lymph node demonstrated multiple histiocytes with emperipolesis with S100 positivity, consistent with Rosai-Dorfman disease.