Paragangliomas and syringomyelia in Tetralogy of Fallot-A case report and literature review

Clin Case Rep. 2024 Oct 16;12(10):e9448. doi: 10.1002/ccr3.9448. eCollection 2024 Oct.

Abstract

Pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries, paragangliomas, and syringomyelia are uncommon diseases. Furthermore, in the absence of any genetic link and with less than five reported adult patients surviving unrepaired rare form of Tetralogy of Fallot, our case shows noteworthiness. The possibility of definitive treatment of these conditions is rendered unsafe due to this persistent defect. Thus, management and ongoing survival of this patient remains complex and challenging.

Keywords: 22q11DS; PA/VSD/MAPCAs; carotid body tumor; cyanotic congenital heart disease; succinate dehydrogenase complex subunit D mutation; syringomyelia.