Synthetic biology in Indonesia: Potential and projection in a country with mega biodiversity

Immanuel Sanka; Ali Budhi Kusuma; Faustina Martha; Andre Hendrawan; Ihsan Tria Pramanda; Adhityo Wicaksono; Afif Pranaya Jati; Maulida Mazaya; Ari Dwijayanti; Nurul Izzati; Muhammad Farhan Maulana; Aulia Reski Widyaningrum

doi:10.1016/j.biotno.2023.02.002

Synthetic biology in Indonesia: Potential and projection in a country with mega biodiversity

Biotechnol Notes. 2023 Feb 28:4:41-48. doi: 10.1016/j.biotno.2023.02.002. eCollection 2023.

Authors

Immanuel Sanka^{1

2}, Ali Budhi Kusuma^{1

3}, Faustina Martha^{1

4}, Andre Hendrawan¹, Ihsan Tria Pramanda^{1

5}, Adhityo Wicaksono^{1

6}, Afif Pranaya Jati^{1

7}, Maulida Mazaya⁸, Ari Dwijayanti¹, Nurul Izzati^{1

3}, Muhammad Farhan Maulana¹, Aulia Reski Widyaningrum¹

Affiliations

¹ Synthetic Biology Indonesia (Synbio.id), Jl. Raya Lintas Sumbawa-Bima, Block AA No. 1, Boak Village, Subdistrict Unter Iwes, 84316, Sumbawa, Indonesia.
² Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.
³ Indonesian Centre for Extremophile Bioresources and Biotechnology (ICEBB), Faculty of Life Sciences and Technology, Sumbawa University of Technology, Jl. Raya Olat Maras Sumbawa, 84371, Indonesia.
⁴ Science Communication Steering Committee, iGEM Foundation, 45 Prospect St, Cambridge, MA, 02139, United States.
⁵ Department of Bio Technology, Indonesia International Institute for Life Sciences (i3L), Jl. Pulomas Barat Kav. 88, Pulomas, Jakarta, 13210, Indonesia.
⁶ Division of Biotechnology, Genbinesia Foundation, Jalan Swadaya Barat no. 4, Gresik, 61171, Indonesia.
⁷ Infection Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria, Australia.
⁸ Research Center for Computing, Research Organization for Electronics and Informatics, National Research and Innovation Agency (BRIN), Cibinong Science Center, Jl. Raya Jakarta-Bogor KM 46, Cibinong, 16911, West Java, Indonesia.

Abstract

Synthetic biology has gained many interest around the globe in the last two decades, not only due to its rapid development but also the potential to provide addressable solutions using standardized design of biological systems. Considering its huge population, biodiversity, and natural resources, Indonesia could play an important role in shaping the future of synthetic biology towards a sustainable bio-circular economy. Here, we provide an overview of synthetic biology development in Indonesia, especially on exploring the potential of our biodiversity. We also discuss some potentials of synthetic biology in solving national issues. Furthermore, we also provide the projection and future landscape of synthetic biology development in Indonesia. In addition, we briefly explain the potential challenges that may arise during the development.

Keywords: Indonesia; Mega biodiversity; Synbio development; Synthetic biology.

Publication types

Review