The number of primary cutaneous lymphoma patients receiving low-dose radiotherapy is increasing, though controlled clinical trials defining the standard radiation dose for each specific entity have not yet been completed. Radiation oncologists are left with making highly individualized decisions that would be better enriched by additional clinical evidence. In this expert opinion, we aim to provide a clear recommendation to improve the current practice of radiation oncology. In addition, existing literature has been reviewed to develop recommendations for all types of primary cutaneous lymphoma. A prospective trial is urgently needed to identify the factors influencing patient outcomes following different radiation doses.
Keywords: Hypofractionation; Leg type; Low-dose radiotherapy; Mycosis fungoides; Primary cutaneous diffuse large B-cell lymphoma; Primary cutaneous follicular centre lymphoma; Primary cutaneous marginal zone lymphoma; Sézary syndrome; Total skin electron beam.
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