ERMCS Ca2+ transmission fuels cell division

Muniswamy Madesh; Neelanjan Vishnu; Dhanendra Tomar

doi:10.1016/j.tcb.2024.10.002

ERMCS Ca²⁺ transmission fuels cell division

Trends Cell Biol. 2024 Oct 21:S0962-8924(24)00208-3. doi: 10.1016/j.tcb.2024.10.002. Online ahead of print.

Authors

Muniswamy Madesh¹, Neelanjan Vishnu², Dhanendra Tomar³

Affiliations

¹ Department of Medicine, Center for Mitochondrial Medicine, University of Texas Health San Antonio, San Antonio, TX 78229, USA. Electronic address: [email protected].
² Department of Medicine, Center for Mitochondrial Medicine, University of Texas Health San Antonio, San Antonio, TX 78229, USA. Electronic address: [email protected].
³ Department of Internal Medicine, Section of Cardiovascular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. Electronic address: [email protected].

PMID: 39438207
DOI: 10.1016/j.tcb.2024.10.002

Abstract

Mitosis is a cellular process that demands high energy, but it was previously unclear how this process is linked with mitochondrial ATP production. Zhao et al. describe how during mitosis, the lamin B receptor migrates to the ER membrane to enhance ER-mitochondria contact sites, coordinating Ca²⁺ surges that increase ATP production necessary for cell division.

Abstract

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