Hepatitis A vaccination coverage survey in 24-month-old children living in Brazilian capitals, 2020

Epidemiol Serv Saude. 2024 Oct 21;33(spe2):e20231162. doi: 10.1590/S2237-96222024v33e20231162.en. eCollection 2024.
[Article in English, Portuguese]

Abstract

Objective: To estimate hepatitis A vaccination coverage in 24-month-old children and identify factors associated with non-vaccination.

Methods: This was a survey involving a sample stratified by socioeconomic strata in capital cities (2020-2022), with coverage estimates and 95% confidence intervals (95%CI), the factor analysis was performed using the prevalence ratio (PR) by means of Poisson regression.

Results: Among 31,001 children, hepatitis A coverage was 88.1% (95%CI 86.8;89.2). Regarding socioeconomic strata (A/B), the variable immigrant parents/guardians was associated with non-vaccination (PR = 1.91; 95%CI 1.09;3.37); in strata C/D, children of Asian race/skin color (PR = 4.69; 95%CI 2.30;9.57), fourth-born child or later (PR = 1.68; 95%CI 1.06;2 .66), not attending daycare/nursery (PR = 1.67; 95%CI 1.24;2.24) and mother with paid work (PR = 1.42; 95%CI 1.16;1.74) were associated with non-vaccination.

Conclusion: Hepatitis A coverage was below the target (95%), suggesting that specificities of social strata should be taken into consideration.

Main results: Hepatitis A vaccination coverage was 88%. Non-vaccination was greater in children with immigrant guardians (strata A/B); of Asian race/skin color, fourth-born child or later, those not attending daycare/nursery and mother with paid work (C/D strata).

Implications for services: The results of this study contributed to the Ministry of Health and Health Departments in monitoring vaccination coverage and identifying factors that may negatively impact hepatitis A vaccination coverage.

Perspectives: Further research is needed on the impact of migration on hepatitis A vaccination and vaccination in general. Health managers should be attentive to the different factors affecting vaccination among social strata.

Objetivo: Estimar cobertura de vacunación contra hepatitis A en niños de 24 meses y identificar factores associados a falta de vacunación.

Métodos: Encuesta en muestra estratificada por estratos socioeconómicos en capitales (2020-2022), con estimación de cobertura e intervalos de confianza del 95% (IC95%) y análisis de factores por la razón de prevalencia (RP) mediante regresión de Poisson.

Resultados: En los 31.001 niños, la cobertura de hepatitis A fue del 88,1% (IC95% 86,8%; 89,2%). Em estratos socioeconómicos (A/B), variable padres/tutores inmigrantes se asoció con la ausência de vacunación (RP = 1,91; IC95% 1,09;3,37); en estratos C/D, variables niño amarillo (RP = 4,69; IC95% 2,30;9,57), cuarto orden de nacimiento o más (RP=1,68; IC95% 1,06;2,66), no asistir a guardería/jardín de infancia (RP = 1,67; IC95% 1,24;2,24) y madre con trabajo remunerado (RP = 1,42; IC95% 1,16;1,74) se asociaron la ausência de vacunación.

Conclusión: Cobertura de la hepatitis A por debajo del objetivo (95%), sugiriendo considerar las especificidades de los estratos sociales.

MeSH terms

  • Brazil
  • Child, Preschool
  • Cross-Sectional Studies
  • Emigrants and Immigrants / statistics & numerical data
  • Female
  • Health Care Surveys
  • Hepatitis A Vaccines* / administration & dosage
  • Hepatitis A* / prevention & control
  • Humans
  • Male
  • Poisson Distribution
  • Prevalence
  • Socioeconomic Factors*
  • Vaccination / statistics & numerical data
  • Vaccination Coverage* / statistics & numerical data

Substances

  • Hepatitis A Vaccines

Grants and funding

National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico - CNPq) – Department of Science and Technology of the Ministry of Health – Process nº 404131 (Vaccination Coverage Survey).