Extracorporeal Support for Acute Respiratory Distress Syndrome

Richard Greendyk; Darryl Abrams; Cara Agerstrand; Madhavi Parekh; Daniel Brodie

doi:10.1016/j.ccm.2024.08.012

Extracorporeal Support for Acute Respiratory Distress Syndrome

Clin Chest Med. 2024 Dec;45(4):905-916. doi: 10.1016/j.ccm.2024.08.012. Epub 2024 Sep 20.

Authors

Richard Greendyk¹, Darryl Abrams², Cara Agerstrand¹, Madhavi Parekh¹, Daniel Brodie³

Affiliations

¹ Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, 622 W168th Street, PH 8E, 101, New York, NY 10032, USA.
² Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, 622 W168th Street, PH 8E, 101, New York, NY 10032, USA. Electronic address: [email protected].
³ Division of Pulmonary & Critical Care Medicine, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 5000, Baltimore, MD 21205, USA.

PMID: 39443007
DOI: 10.1016/j.ccm.2024.08.012

Abstract

Extracorporeal life support (ECLS) has a long history in the management of the acute respiratory distress syndrome (ARDS). The objectives of this review are to summarize the rationale and evidence for ECLS in ARDS including its role in reducing ventilator-induced lung injury (VILI), suggest best practice management strategies during ECLS, and identify areas that require additional research to better inform patient care.

Keywords: Acute respiratory distress syndrome; Extracorporeal carbon dioxide removal; Extracorporeal life support; Extracorporeal membrane oxygenation; Lung-protective ventilation.

Publication types

Review

MeSH terms

Extracorporeal Membrane Oxygenation* / methods
Humans
Respiratory Distress Syndrome* / physiopathology
Respiratory Distress Syndrome* / therapy
Ventilator-Induced Lung Injury / prevention & control