Abstract
We report the first case of biopsy-proven primary hepatic amyloidosis in which histologic regression was demonstrated after therapy with melphalan and prednisone. On the basis of the cumulative reported experience regarding the treatment of this rare plasma cell dyscrasia, we recommend a trial of cytotoxic therapy for patients with primary hepatic amyloidosis.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Amyloidosis / drug therapy*
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Amyloidosis / pathology
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Amyloidosis / physiopathology
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Female
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Humans
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Liver Diseases / drug therapy*
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Liver Diseases / pathology
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Liver Diseases / physiopathology
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Male
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Melphalan / therapeutic use*
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Middle Aged
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Prednisone / therapeutic use*