[Postoperative outcome of special primary aldosteronism undergoing surgery based on adrenal vein sampling results]

Zhonghua Yi Xue Za Zhi. 2024 Oct 29;104(40):3775-3779. doi: 10.3760/cma.j.cn112137-20240518-01139.
[Article in Chinese]

Abstract

To further demonstrate the gold standard role of adrenal vein sampling (AVS) in the subtyping diagnosis of primary aldosteronism (PA). In this study, 9 patients with special PA, whose functional advantages indicated by AVS were contrary to the results of CT examination, were selected. Laparoscopic adrenalectomy was performed based on AVS results, and the surgical outcome was followed up. Nine patients, aged[M(Q1, Q3)] 58.0 (52.0, 63.0) years, including 7 males and 2 females, were followed up for 12 (9, 12) months. CT revealed unilateral morphological abnormalities in 5 cases (the functional advantage side indicated by AVS was contrary to the results of CT examination), and bilateral abnormalities in 4 cases (AVS results confirmed unilateral abnormalities). During the follow-up, all 9 patients achieved complete biochemical remission, 4 patients achieved complete clinical remission, and 5 patients achieved partial clinical remission. The study indicates that compared with CT imaging, AVS has better accuracy in PA subtyping, and selecting surgical side based on AVS results is a reliable and effective strategy.

为进一步论证肾上腺静脉采血(AVS)技术在原发性醛固酮增多症(PA)分型诊断中的金标准地位,本研究筛选9例特殊的PA患者,即AVS证实的功能优势侧别与CT检查结果相反,基于AVS结果实施病变侧别的腹腔镜肾上腺切除术,并完成手术结局随访。9例患者年龄[MQ1Q3)]58.0(52.0,63.0)岁,男7例,女2例,随访时间12(9,12)个月,CT单侧形态异常5例(AVS证实的功能优势侧别与CT检查结果相反),双侧4例(AVS结果证实为单侧)。随访期内,9例患者全部获得了生化完全缓解,4例临床完全缓解,5例临床部分缓解。研究表明,与CT相比,AVS技术对PA分型诊断具有更好的准确性,基于AVS结果选择手术侧别是一种可靠、有效的策略。.

Publication types

  • English Abstract

MeSH terms

  • Adrenal Glands* / blood supply
  • Adrenalectomy* / methods
  • Female
  • Humans
  • Hyperaldosteronism* / surgery
  • Male
  • Middle Aged
  • Treatment Outcome
  • Veins