Growing microglia in the lab

Elife. 2024 Oct 28:13:e103535. doi: 10.7554/eLife.103535.

Authors

Jonathan M Levenson¹, Hio Tong Kam², Dong Feng Chen²

Affiliations

¹ FireCyte Therapeutics, Inc, Boston, United States.
² Schepens Eye Research Institute of Mass. Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, United States.

Abstract

Transplanting microglia derived from human stem cells into mice reveals new possibilities for treating neurodegenerative eye diseases.

Keywords: Microglia; NaIO3; PLX-5622; RPE; human iPSC; mouse; regenerative medicine; retinal transplantation; stem cells.

© 2024, Levenson et al.

Publication types

Editorial

MeSH terms

Animals
Humans
Mice
Microglia* / physiology
Neurodegenerative Diseases / pathology
Neurodegenerative Diseases / therapy