Researchers frequently come across sample size calculations in the scientific literature they read, in projects undertaken by their peers, and likely within their own work. However, despite its ubiquity, calculating a sample size is often perceived as a hurdle and not fully understood. This paper provides a brief overview of sample size estimation to guide readers, researchers, and reviewers through its fundamentals.
Keywords: clinical trials; epidemiology; observational research; power analysis; sample size calculation.
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