Community standards and future opportunities for synthetic communities in plant-microbiota research

Nat Microbiol. 2024 Nov;9(11):2774-2784. doi: 10.1038/s41564-024-01833-4. Epub 2024 Oct 30.

Abstract

Harnessing beneficial microorganisms is seen as a promising approach to enhance sustainable agriculture production. Synthetic communities (SynComs) are increasingly being used to study relevant microbial activities and interactions with the plant host. Yet, the lack of community standards limits the efficiency and progress in this important area of research. To address this gap, we recommend three actions: (1) defining reference SynComs; (2) establishing community standards, protocols and benchmark data for constructing and using SynComs; and (3) creating an infrastructure for sharing strains and data. We also outline opportunities to develop SynCom research through technical advances, linking to field studies, and filling taxonomic blind spots to move towards fully representative SynComs.

Publication types

  • Review

MeSH terms

  • Agriculture
  • Bacteria / classification
  • Bacteria / genetics
  • Microbiota*
  • Plants* / microbiology
  • Synthetic Biology / methods