Letter to the Editor: Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection

HGG Adv. 2024 Nov 2:100382. doi: 10.1016/j.xhgg.2024.100382. Online ahead of print.

Abstract

Research into HLA-B*15:01 association with asymptomatic SARS-CoV-2 infection has so far yielded contradicting results. Using the UK Biobank cohort, we found a significant association between HLA-B*15:01 and asymptomatic infection. Our study adds more evidence for the complex role HLA alleles play in SARS-Cov-2 infection severity.

Publication types

  • Letter